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There are many answers to this and we will try and cover at least some of them. So, what exactly are these medications that were discovered unintentionally and also have been used worldwide as a cure for certain ailments? Doctors have used BH4 and diets that exclude phenylalanine for almost a decade to treat PKU, a so-called inborn error of metabolism that if left untreated causes irreversible brain damage. In PKU, this enzyme coworker helps break down the molecule phenylalanine whose buildup is toxic to the brain. Researchers say this is the only form of the enzyme that functions normally, making more nitric oxide rather than free radicals. Add-on drugs include vitamin C or folic acid, both of which are known to interact with the so-called enzyme cofactor, and researchers plan to monitor closely for the effects of combined therapy on heart function, size and weight. The high-tech imaging allowed investigators to see microscopic injury to the cones of the retina, the cells which are responsible for color vision. OCT is an advanced imaging system that reveals the cross-sectional details of the retina layer by layer. Mount Sinai researchers used state-of-the-art technology, including adaptive optics (AO) and optimal coherence tomography (OCT), to examine his retina for evidence of structural damage at the cellular level, something that had never been done before. Richard Rosen, MD, Director of Retina Services at New York Eye and Ear Infirmary of Mount Sinai (NYEE). In a first-of-its-kind study, Mount Sinai researchers have shown that color vision problems caused by retinal damage on a cellular level can result from a high dose of sildenafil citrate, the popular erectile-dysfunction medication sold under the brand name Viagra. Protein kinase G is also the target of drugs like sildenafil (commonly known as Viagra). He reported that his symptoms began shortly after taking a dose of liquid sildenafil citrate that he purchased over the internet (sildenafil citrate can cause visual disturbances with normal dosage, but symptoms typically resolve within 24 hours). Aging is not the biggest cause of erectile dysfunction as some would have you believe. As such, the risk that the drug could cause congenital malformation is minimal. According to the American Heart Association, more than 65 million American adults have high blood pressure, a major risk factor for developing larger-than-normal hearts. Hypertrophy increases by two to three times an adult’s risk of suffering cardiovascular disease, including heart failure and sudden cardiac death. Improvements with BH4 therapy were almost as dramatic in at least three other measurements of organ health, including heart wall thickness, muscle cell size and fibrosis, and lowered chemical production of dangerous free radicals. Do three sets of pelvic contractions twice everyday. Once Evans had completed his radium measurements, he returned Byers' bones to their lead coffin in Pittsburgh, where they remain to this very day, as radioactive as ever. Evans was an expert at measuring and mathematically modeling the human body's uptake and excretion of radioactivity. Based on Byers' self-reported RadiThor consumption, Evans' model had predicted that Byers' body would contain about 100,000 becquerel of radioactivity. Over time, the radium delivered a whopping radiation dose to Byers' skeleton. When Byers died, he was put to rest in a lead-lined coffin, to block the radiation being released from the bones in his body. If the original Sont Ericsson Xperia X10 and its smaller version impressed you, then rest assured the the Sony Ericsson Xperia X10 Mini Pro also will not disappoint you. No use caring topically for your skin then filling your body with fried food, cakes and chocolate, eat healthy too ! The patient was then diagnosed with persistent retinal toxicity linked to the high dose of medication damaging the outer retina. Rosen and a team of investigators from NYEE based their study on a 31-year-old patient who arrived at an urgent care clinic complaining of red-tinted vision in both eyes that hadn't gone away in two days. 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